Dritan Useini*, Justus Strauch
Useini et al. J Clin Transl Res 2022; 8(4):6
Published online: July 25, 2022
Background & aim: Some transcatheter aortic valve implantation (TAVI) candidates present with ubiquitary arterial disease with massive calcification burden and stenoses in the whole arterial tree and cannot undergo any transvascular TAVI-approach. Moreover, a history of previous coronary surgery including LIMA-LITA in situ bypass grafting, previous carotid surgery or stenosis /occlusions, a concomitant porcelain aorta, Leriche syndrome, diverse other aortic diseases, arterial occlusions, or a chronic dialysis with arteriovenous shunt are common in such patients with end-stage peripheral artery disease, making even a minimal artery access impossible. For patients without arterial access or at very high risk for artery injury, we modified the transapical-TAVI method to ensure artery-no-touch-technique. We employed this technique in six patients without procedural and in-hospital complications.
Relevance for patients: A high-grade aortic stenosis is a serious disease. Untreated patients exhibit poor survival. Only surgery or TAVI are valid therapy concepts for treatment. However, some patients can undergo neither surgery nor TAVI, because of an extensive surgical risk or inoperability, whereas at the same time no arterial approaches are available due to extensive, end-stage panarteriopathy. For these high-specific patients our modified, artery-no-touch-TA-TAVI is an appropriate method and can be safely used.
1. Department of Cardiothoracic Surgery, Ruhr-University Hospital Bergmannsheil, Bochum, Germany
2. Department of Cardiovascular Surgery, Herz-Kreislauf-Zentrum, Rotenburg a. d. Fulda, Germany.
* Corresponding author
Department of Cardiothoracic Surgery, Ruhr-University Hospital Bergmannsheil,
Bürkle de la Camp Platz 1; 44789 Bochum, Germany
Tel.: +49 17641744123; +49 234302 3026
Fax: +49 234 302 6010;
Department of Cardiovascular Surgery, Herz-Kreislauf-Zentrum, Rotenburg a. d. Fulda, Germany.
36199 Rotenburg a. d. Fulda Germany
Tel. +49 662 388 5858
Fax +49 662 388 5860
Department of Pharmaceutics, Utrecht University, the Netherlands
Department of Pharmaceutics, Jiaxing University Medical College, Zhejiang, China
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